Hi, I'am planning a level inside ue4 and I would like to use vertex painting on walls to blend multiple materials together. I do know that I'll need a fair amount of vertexes to have nice results when blending the materials, but, should I disable LODs for assets that will have vertex painting ?
If you're talking about walls and floors that are basically just planes /boxes or other simple geometry with a few verts added for painting there's not much point in lodding them. Lodding anything architectural with under a couple of hundred tris is of dubious value unless you can see a shit load of them at once.
LODs are an optimization technique, if you disable them you might have terrible performance, besides sth called 'overshading' which is a uggly visual glitch, but disabling LODs might be okay for short distances like interior scenes. Idk about vertex painting in UE, but why don't use ordinary baked textures instead?