I had a chance to use 21:9 in a three monitor setup for a couple weeks, was really pointless and ended up turning one of the monitors off and made my eyes tired.
I spent some time screenshotting my setup of 3D and other programs that I use to make game art. I couldn't find anything like this when researching ultrawides before purchase so I just want to share some examples. Imgur album:http://imgur.com/a/LwJfk
I've a 21:9 @2560x1080 and a 4:3 to the left. I rarely use the left side, and mostly for floating panels in maya. I'd say it's mostly comfy, but keeping reference to the side gets my neck sore after a while so I just stick with the main. Maybe if they were larger I'd be better off pushing them back farther from me.
I'm used to having 2 x 27" but I just bought an LG 34UM88C-P (34" 21:9) It's fantastic, even wit hless overall real estate its more than enough for my needs in most programs and 'feel's more spacious. I won't be going back to 2 screens anytime soon. Only 'issue' I've had is with trying to make a good UI for ZBrush. I don't…
My Dell monitor only has a minor curve so it hasn't bothered me at all, and everything has grids and guides anyways. And I have retired the second monitor, so I'm just on the single ultrawide now and no looking back.
Yeah I almost don't need the second monitor anymore. I've been using refboard made by someone here which is an always on top image viewer. The setup had been working pretty well.