For my project need to be able to change by scripting the materials properties.
Looking at Megascans as potential source for base materials I can use to derivate a new set, want to know where I'm starting from, so if there is any documentation about the base value used to create these materials.
Since Mixer it's not scriptable I wil need to change the materials in another tool, starting with them as base reference.
There is any structured materials parameters database from whom I can start from.
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I'm not entirely sure what you're asking here - it seems like you might be asking for a method to change the material properties of the scans in Mixer? This is unfortunately not possible, scanned data is solidified and not something that can be changed into a completely different material as though it had editable layers, at least not without modifying the texture using the Mixer app to blend it and work with it.