What do I need to do this?

Guapamolee

https://www.youtube.com/watch?v=_XG9eHu57wE

To make 3D models like the girls, what would it take to Model them and animate them.

I have some knowledge on 3D models and how to animate 3D models, but its there any program that you would recommend for this? Is there any tips you have to make this process go smoothly?

Burpee

The only thing that 'd help you I'd say is a good toon shader ! I don't know about real time engine, but vRay and Arnold both has pretty solid toon shader.
Cheers!

RN

@Guapamolee you're in luck, there's tons of reference online on how to make 3D anime characters. You just need to know where to look:

SketchFab, to inspect model wireframes and textures: https://sketchfab.com/xkungwork

Collectible figures, for reference on how to sculpt something that was originally 2D only: https://imgur.com/a/mJBVAUk

You can find technical reference by searching for 3DCG terms in Japanese (use google translator), like "3D anime model wireframes" etc.

RN

 Oh, there was also a nice thread by @ADR where they talk about Euclid, an animation software from company Live2D: https://polycount.com/discussion/186373/2-5d-character-models