It depends entirely on how close the camera gets (kinda like VFX, I suppose), but assuming its AAA quality third person you might have 2-3 4K texture sets (*super ball-park guesstimate, I am not a character artist), with multiple layered tiling textures on top that are blended with mask textures which give you the super…
This is in the wrong forum section, just for future reference... ... are you using ZBrush 2? That matcap looks like the ZBrush 2 one, brings me back...