So this is a big question I have been thinking about lately. What 3D programs are critical in working in the game modeling biz? I've heard that many companies use 3DS Max and that Maya is used for animation. I was also recommended XSI. I already know how to model in Maya, but is it necessary for me to learn Max and XSI or some other program too? What about programs like mudbox and zbrush?
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alexk covered the sculpting stuff.
As for the other programs: XSI has decent industry penetration in Japan and Europe, but is still playing catchup in the US. Silo is starting to gain some popularity as is Modo, but they're still years away from widespread use. Blender has essentially any tool you'd want, but I've yet to hear of a game studio that uses it, and its interface is far from standard.