Zbrush - Importing "The topology of the mesh has changed"

Nerono

I want to import an object into zbrush but when I do it has this message pop up, which wont allow me to import the mesh I want, help :0

cryrid

Use the Subtool Master plugin to Multi-Append your obj instead. 

pior

Click the star model (or any other default model really), then import. This should reset it.

musashidan

And yet another option is to exit edit mode, ctrl+N to clear the canvas, import the .obj

The reason you're seeing that message is because ZB assumes you're importing a version of the active mesh that you may have edited elsewhere and now want to propogate those edits, i.e: new uvs, topology changes, etc.