Quixel Vs Substance

Seiyaru

So whats the main difference? Pro's and Cons. What they're used for primarily since I know some programs have primary usage differences. Also for Quixel the video I watched below has programs or things like 3DO as he called it, and used Photoshop as well. Will I need access to Photoshop and or a 3rd program (3DO?) to use Quixels stuff effectively?

http://quixel.se/hub/tutorial/ddo-painter-for-beginners-azog-breakdown/

Sorry, am new to the texturing side of things. I model but wanna move into texturing more now to make my stuff look far more acceptable. Thanks guys!