I knew H.264 was our best bet, but it's just not rendering out as well as I would have thought from Sony Vegas. We'll try rendering out to tifs and using that Adobe Media Encoder to see what results we get. Any other suggestions?
definitely render out in single frames, or uncompressed (or any other lossless) and then use the tool of your choice to compress it (e.g. Super, Mediacoder, Premiere, Moviemaker) - after all you don't want to render it out again if some settings don't work for you. H.264 is probably one of the widest supported formats,…