If you still have any problems with spikes in the mesh, try saving a morph target before projecting. Then switch back to the unprojected mesh in the morph target menu and paint back in the projection with the morph brush.
Have you messed around with the project all settings? I usually lower the Mean to fix this kind of stuff, I also often bulge the target mesh out so that it is always larger than the reference mesh.
Thanks Bal: Yeah. I've played with the settings a bit and I inflated the target mesh. If I lower the mean I get a slightly better result between the fingers but the finger tips are still inverted. Could this be something to do with the normals created by the ZSphere mesh? I also tried projecting from the lowerest sub…