Ohhh yeah, good point. That Trauma Center was a BITCH of a hard game, for the ENTIRE second half. Each surgery you thought couldn't get harder, but it DID. And each type of guilt got more annoying than the last. And then, THEN, you've finally made it to the final boss... and what is the final boss? IT'S EVERY GODDAMN GUILT…
I do remember Alma being pretty tough in Ninja Gaiden way back when. I actually was never able to finish the game, but it was well past Alma that I got stuck and I don't think that it was on a boss fight. Demon's Souls has Maneater.... Maneater is incredibly hard if you have a melee oriented character because you can't hit…