If your game engine uses the substance SDK then wouldn't it look very close? I understand there will always be differences between render engines due to tonemapping and hdrs not perfectly matching. But the difference might not be that notice-able. For instance naughty dog seems to have custom brdf nodes written for…
These threads have always been popular with the hard surface + texturing themes but I reckon it would also work really well with substance designer/painter. So either post what your looking to make or some shots / explanations of your substance - might requite a little explanation on the image as to the process and what…