I wonder how much you'll be able to tweak the parameters? For example, a preset that allows you to achieve a hand painted look... reminds me a bit of a photoshop filter. I'm looking forward to it.
CS6 has been the only PS not to bog me down so far with nDo open, I did some tests with earlier version, and it's a PS problem from what I figured. It also helps if you work only on one texture at a time, and have only the textures you need displayed on the mesh. I also hope dDo has some shader specific baking options,…