Update with initial wires, only half concerned with edge flow right now. Also discovered the graphite loop tools, specifically straighten, which should allow me to work faster and then straighten out any odd edges.
From what I can see, the side of the leg and knee area are very messy and have some edges that don't contribute neither to deformation nor silhouette. To imrpove your edge loops, you should study human form and notice the way muscles flow on it, and use the edges to emphasize that flow. Maybe this page might help you with…