It really depends on what you're doing, I mean I've wrote pages and pages on the topic now, when you want to step up to better lenses, prime lenses, etc its going to be a major problem. If you just want to stick with the cheap AF-S zooms, its not really a big deal. For me it would be a massive problem. Macro is another…
I was more talking about specific styles/types, so like: Sports? Weddings? Portraits? Landscapes? Cityscapes? Interiors? Low light bars/clubs with friends? Low light exterior/nightscapes? Pets/birds? Vacation snapshots in daylight? Long exposures, for waterfalls etc? The specific sort of things you want to do will tend to…