Can you sculpt on a model with UV in ZBrush, then edit the UV to accommodate the modified mesh?

Bit of a long description for a simple question, but I recently purchased a bunch of alien creatures to use in a VR game I'm trying to develop, and I was wondering how would I go about editing some of them in ZBrush? They're FBX files, and I've managed to successfully import one into ZBrush with textures and UV maps intact, but I don't know if you can sculpt or paint on the model, then adjust the existing UV map to accommodate the change in the mesh surface and texture change?