really really noob sculpting/mudbox question

so I'm going to try and whip together an entry for the mudbox competition as I've started to get pretty decent with it, and I realized I don't really know the answer to something

so I take a base mesh for a character and unwrap it, import it into mudbox and being to sculpt and paint it, it's done and it's awesome

How concerned should I be with the level of detail for the sculpt I do in regards to the UV's and overall complexity of the base mesh?

If I worded this really stupid let me know and I'll try and readdress it

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